Viruses transmitted by mosquitoes or other arthropods, the so-called arboviruses, are a substantial threat to the health of humans and animals worldwide. They can cause severe diseases such as hemorrhagic fever, encephalitis and chronic arthritis. Due to increased travelling, climate change and adaptation of arthropod vectors to urbanization, the global human and animal population at risk for mosquito-borne diseases is expanding. Despite the significant disease burden and widespread presence, antiviral drugs and (efficient) vaccines are not available. Improving global preparedness for arboviruses is thus of utmost importance.